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The Potential Benefits of Spermidine Supplementation on Sleep

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The Potential Benefits of Spermidine Supplementation on Sleep

Spermidine & Cellular Senescence

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Spermidine & Cellular Senescence

As part of our continued exploration of how spermidine influences the 12 hallmarks of aging, this article focuses on the 8th: cellular senescence. This hallmark refers to a state of...

Spermidine: Science’s Safest Choice for Lifespan Extension

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Spermidine: Science’s Safest Choice for Lifespan Extension

Longevity compounds need to be especially safe because they’re intended for generally healthy people who may take them over long periods of time. Unlike treatments for acute or life-threatening conditions,...

Spermidine: The Unsung Hero Behind Rapamycin’s Longevity Boost

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Spermidine: The Unsung Hero Behind Rapamycin’s Longevity Boost

Rapamycin often steals the spotlight in longevity research, and for good reason. It’s a leading compound known to extend lifespan across species. Yet, quietly supporting rapamycin’s effects is another molecule:...

Spermidine & Mitochondrial Dysfunction

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Spermidine & Mitochondrial Dysfunction

As part of our continued exploration of how spermidine influences the 12 hallmarks of aging, this article focuses on the 7th hallmark: mitochondrial dysfunction.Aging is a multifaceted biological process marked...

New Study Reveals Powerful Duo for Longevity: Spermidine + Protein Restriction

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New Study Reveals Powerful Duo for Longevity: Spermidine + Protein Restriction

Aging is a natural process involving gradual decline in cellular and tissue function, leading to reduced regeneration and increased disease risk. Rather than just wear and tear, aging results from...

Spermidine vs. Estrogen: A Natural Alternative for Cardiometabolic Health After Menopause

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Spermidine vs. Estrogen: A Natural Alternative for Cardiometabolic Health After Menopause

For women, menopause marks not just the end of fertility, but the beginning of an increased risk for cardiometabolic disease. The sharp drop in estrogen that occurs during this time...

Spermidine & Deregulated Nutrient Sensing

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Spermidine & Deregulated Nutrient Sensing

As we continue exploring the 12 hallmarks of aging, we turn our attention to the sixth: Deregulated Nutrient Sensing. This hallmark reflects how aging cells lose their ability to correctly interpret...

How Spermidine Supports Hormonal Balance in Women

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How Spermidine Supports Hormonal Balance in Women

We often highlight spermidine’s benefits for cognitive and cardiovascular health—but did you know it also plays a key role in supporting hormonal balance? Let’s take a closer look. Why hormonal...

Spermidine & Disabled Macroautophagy

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Spermidine & Disabled Macroautophagy

Aging is a multifaceted biological process marked by the gradual decline of cellular and organismal functions. Among the hallmarks of aging, disabled macroautophagy plays a critical role in age-related deterioration....

The Benefits of Spermidine for Your Skin: A Natural Wonder

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The Benefits of Spermidine for Your Skin: A Natural Wonder

Is there any area where natural spermidine supplementation doesn’t deliver a benefit? We haven’t found one yet! Spermidine—a naturally occurring polyamine present in all living organisms and abundant in foods...

How Much Spermidine is in Semen?

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How Much Spermidine is in Semen?

After working with spermidine long enough to know its levels in wheat germ, broccoli, and aged cheese by heart, I have a confession: I never actually knew how much spermidine...

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12 hallmarks of aging allergy autophagy brain health cosmetic dental health diabetes diet fasting featured fertility gluten hair health heart health immune health inflammation longevity metabolism press primary women's health