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What Is Spermidine? All You Need to Know
As we get older, many of us naturally begin to focus more on health and longevity. If you keep up with health trends, you may have heard of one particular molecule of interest - spermidine. Increasing spermidine intake through your diet has been attributed to a longer and healthier life.
Spermidine is a fascinating compound. And until recently relatively little was known about spermidine's role in longevity. Within the last 10 years researchers have linked spermidine to longer healthspans and better aging.
We now know that spermidine is a unique, naturally occurring molecule, part of a group of molecules known as polyamines. Polyamines interact with our cells to perform various critical metabolic functions.
Spermidine is found in all plants and animals and in nearly every cell of your body. In our bodies, it can come from ingested food - synthesized in the gut microbiome or synthesized in cells. Spermidine is most abundant in wheat germ. -
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Add Spermidine to Your Diet
您知道吗？
相关的研究表明，我们体内的亚精胺水平大约是在25-30岁开始出现下降。
但是，最近在知名的“蓝区（Blue-Zones）”进行的一项研究表明，这一地区90岁和100岁老人体内的亚精胺水平与年轻人体内的亚精胺水平大抵相当。
这一现象令人兴奋，对吗？ -
为什么亚精胺如此重要？
人体能够分解和回收不必要的、或者已受损的细胞成分。这一更新过程被称为“自噬”。
自噬能够使我们的细胞保持年轻，并让我们免受许多疾病的侵害。大量科学研究表明，随着我们年龄的增长，自噬进程会停滞。但是，通过禁食，和/或补充亚精胺，我们可以轻松地抵抗这种趋势。
相关的研究发现，增加亚精胺的摄入量具有类似禁食的强大功效。由于我们细胞中的亚精胺含量会随着时间的推移而减少，我们只能依赖于亚精胺补充剂和富含亚精胺的食物。
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What Does Spermidine Do?
Spermidine plays an essential role in organisms, like humans and even plants. One of spermidine's biggest and most profound functions, from which other functions stem from, is the ability to counteract aging and promote autophagy.
Our bodies are made up of cells. As we age, our cells age as well. When these cells become old or damaged, it can cause build up of dead or toxic organelle matter in our bodies, potentially leading to age-related disease and injury. Spermidine in our cells optimizes autophagy and cellular renewal.
Spermidine is also known to regulate various cellular processes including:
- DNA Stability
- Cellular growth
- Cellular differentiation
- Apoptosis (Which is cellular death as a normal part of growth and development in organisms)
Research in treating aged mice with spermidine found that it led to a decrease in arterial stiffening, which is an aging-related condition correlated to the deterioration of autophagy.
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How Can Spermidine and Autophagy Help Our Body?
When you hear that autophagy is basically cells cannibalizing one another, it’s easy to think that it sounds harmful to your body. However, autophagy is quite beneficial and something scientists believe you should be striving for on a regular basis. While it’s still unclear how exactly autophagy creates some of these benefits, here are some benefits of autophagy:
- Removing toxic proteins from the cells that may be a cause of some age-related diseases
- Recycling residual proteins
- Providing energy and building blocks for cells
- Promoting regeneration and healthy cells
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针对亚精胺的研究
大约10年前，奥地利“格拉茨大学（University of Graz）”的一个研究小组发现了亚精胺具备触发自噬的功能。这个小组是由Frank Madeo教授兼博士负责的。
自从这一革命性的发现以来，约有100个国际研究团队一直在研究这种物质，以及它对健康的益处。
从科学调查的角度来讲，这项研究仍处于早期阶段。但是，几乎没有对哪种物质的研究比对亚精胺的研究更深入。
有一件事是肯定的：
对于我们了解活体细胞如何发挥功能，以及衰老进程来说，这些研究结果可能会产生重大影响。 -
Frank Madeo 教授兼博士
Madeo 博士是奥地利“格拉茨大学(University of Graz)”分子生物学研究所的一名教授，正是他发现了亚精胺是一种自噬触发器。他是spermidineLIFE® 亚精胺补充剂的“研究之父”，也是“长寿实验室（ Longevity Labs+）”咨询委员会的成员。
有关亚精胺和自噬的最新研究进展
为什么亚精胺如此重要？
富含亚精胺的饮食对我们的健康非常重要。幸运的是，相当多的食物中都含有亚精胺，比如：蘑菇、大豆、坚果，尤其是小麦胚芽。
但是，不同食物中的亚精胺含量差别很大。因此，生物利用度的问题（即：通过富含亚精胺的食物来吸收的问题）目前尚无定论。
spermidineLIFE® 亚精胺补充剂经过了严格的临床测试，并已通过外部实验室的确认。因此，其亚精胺的高含量是有保证的。
亚精胺能够促进您和您的细胞健康。