Getting Started With spermidineLIFE®

As with many of our new customers, you probably have a lot of questions! How do I take it? When do I take it? How do I store it? What should I feel? We're here to help. Below are resources we've gathered to help answer your questions and help you get started with spermidineLIFE®.

spermidineLIFE® Best Practices

As a general recommendation, we suggest taking two (2) capsules at the same time every day with a sufficient amount of liquid to wash down the capsule, as with many naturally derived dietary supplements we also recommend that you take spermidineLife with a meal to facilitate proper digestion. Taking the capsules at the same time each day ensures consistent supplementation.
Although we have found the best results from those who take spermidineLife in the morning, we encourage you to find the best time of day that works for you and your schedule.

How Long Should I Take spermidineLIFE®?

The recommended dosage of spermidineLIFE is one milligram spermidine per day (2 capsules of spermidineLIFE®), this is considered a “maintenance” dose of spermidine, which is safe to take daily for as long as you wish. Increased levels of spermidine and polyamines will begin to take effect on a cellular level from day one. We recommend beginning with a 60-day cycle to allow your cells to adjust to higher spermidine levels and the enhanced autophagy benefits.

If you choose to routinely “cycle” spermidineLIFE (i.e., not taking consistently), we recommend cycling with a minimum of 60-day cycles (meaning 60-days on, following with 30-days off, and so forth). Our cells do not adjust as fast as one might imagine, to consistent changes in diet. Just as you may not see or feel the benefits of a change in diet over a 24-hour period, you will not see or feel the benefits of a dietary supplement over one 24-hour period.

When will I feel the effects of spermidineLIFE®?

Each and every one of our body’s intestinal microbiota and physiology are different. We have different diets, ages, health profiles, cellular stress levels, and health habits. Autophagy leads to a normalization of cell function through breaking down unused cellular matter, resulting in increased cellular efficiency and function. This micro-change in our bodies can manifest in many different ways. For some, particularly those with health profiles that lead to consistent autophagy anyway, there may be little to no noticeable physiological changes within a 30-60 day cycle. This does not mean spermidine is doing nothing, it is simply further enhancing your healthy cellular lifestyle, which may not necessarily be a “change” for the healthiest among us. We know that spermidine levels decrease significantly with age, so older populations tend to “feel” spermidine supplementation faster and more acutely than younger populations. That being said, spermidine supplementation at a younger age can increase cellular health into older age, a “key” to cellular longevity.

From our research and anecdotal reports, users may experience any of a number of the following noticeable physiological changes from improving cellular health through spermidine supplementation:

- Increased hair/nail growth

- Increased energy

- Decreased inflammatory markers, often associated with point-specific injuries or cellular damage

- Increased mental clarity

- Increased deep sleep (as a proportion of overall sleep)

- Increased sexual health markers (yes, our cells play a role in this too!)

- Increased immune-efficiency

This list is ongoing, both in research and in anecdotal reports. If you find something specific, drop us a line and let us know your own experience with spermidineLIFE®!

How do I Store My spermidineLIFE®?

SpermidineLIFE® will remain shelf-stable for 16 months or longer, when stored in its original container in a cool, dry place. Furthermore, you can store spermidineLIFE® in the refrigerator to maintain the most stable product.

Prolonged exposure to direct sunlight, high humidity, or high temperatures (above 77 degrees Fahrenheit) can lead to degradation in the appearance and color of the extract, however, current studies show no loss of effectiveness in the product after exposure.

Will taking spermidineLIFE® break my fast?

Officially, we must advise that you seek advice from a healthcare practitioner on this topic. Additionally, as you may find in your own research on the topic, the science is still not clearly settled on what exact type and amount of calories kicks our bodies out of autophagy.

That being said, it is generally recognized that the trigger for “ending” a fast is when the body creates an insulin response. While most of the contents of spermidineLIFE® clearly fall into the healthy fats category of the food groups, there is a tiny amount of carbohydrates in spermidineLIFE®, approximately 5mg per serving. From our early research, this volume is generally insufficient to trigger an insulin response; thus, spermidineLIFE® should not be considered a fast “breaker.”

Fasting practices and principles very widely and are based on a number of scientific and non-scientific principles. For many, fasting means more than caloric restriction: it can be a mental, spiritual, religious, and physical experience. Accordingly, if you choose to fast out of principles beyond simply caloric restriction, choosing to take supplements during a fast is a personal choice.

Remember, spermidine has been shown to trigger and enhance autophagy. As such, even though there is a small number of calories contained in spermidineLIFE®, the benefits of enhanced autophagy may easily outweigh the risks of a small caloric intake. At this point in the global research community, there is not a clear, settled answer to this yet.

We believe spermidineLIFE® is perfectly safe to take during intermittent or extended fasting (just not dry fasting). If you want to hedge your bets during your fast, take spermidineLIFE® (and your other supplements!) before you fast and/or after. During an extended fast, you may choose to abstain (again, personal preference here).

Can I open the spermidineLIFE® capsules and take with food or liquid?

Absolutely! spermidineLIFE® capsules can be opened and the pure extract can be mixed with ROOM TEMPERATURE or COLD foods and beverages. The taste is quite tolerable — a little sweet a little salty tasting.

We do not recommend adding to hot beverages such as coffee or tea or hot foods like soups. Polyamines are quite delicate and heat can damage polyamine content (research is ongoing how this impacts polyamine-containing foods during food preparation).