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Spermidine & Altered Intercellular Communication

autophagy

Spermidine & Altered Intercellular Communication

Spermidine & Stem Cell Exhaustion

autophagy

Spermidine & Stem Cell Exhaustion

As part of our continued exploration of how spermidine influences the 12 hallmarks of aging, this article focuses on the 9th: stem cell exhaustion. Aging is a complex biological process...

Spermidine: The Unsung Hero Behind Rapamycin’s Longevity Boost

autophagy

Spermidine: The Unsung Hero Behind Rapamycin’s Longevity Boost

Rapamycin often steals the spotlight in longevity research, and for good reason. It’s a leading compound known to extend lifespan across species. Yet, quietly supporting rapamycin’s effects is another molecule:...

Spermidine & Mitochondrial Dysfunction

autophagy

Spermidine & Mitochondrial Dysfunction

As part of our continued exploration of how spermidine influences the 12 hallmarks of aging, this article focuses on the 7th hallmark: mitochondrial dysfunction.Aging is a multifaceted biological process marked...

How Spermidine Supports Hormonal Balance in Women

autophagy

How Spermidine Supports Hormonal Balance in Women

We often highlight spermidine’s benefits for cognitive and cardiovascular health—but did you know it also plays a key role in supporting hormonal balance? Let’s take a closer look. Why hormonal...

Spermidine & Disabled Macroautophagy

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Spermidine & Disabled Macroautophagy

Aging is a multifaceted biological process marked by the gradual decline of cellular and organismal functions. Among the hallmarks of aging, disabled macroautophagy plays a critical role in age-related deterioration....

The Benefits of Spermidine for Your Skin: A Natural Wonder

autophagy

The Benefits of Spermidine for Your Skin: A Natural Wonder

Is there any area where natural spermidine supplementation doesn’t deliver a benefit? We haven’t found one yet! Spermidine—a naturally occurring polyamine present in all living organisms and abundant in foods...

How Spermidine Can Help Treat Diabetic Periodontitis

autophagy

How Spermidine Can Help Treat Diabetic Periodontitis

Periodontitis is a chronic inflammatory condition that not only damages your gums but gradually erodes the very structures anchoring your teeth. It is a common complication in individuals with Type...

Spermidine & Epigenetic Alterations

autophagy

Spermidine & Epigenetic Alterations

The third hallmark of aging is epigenetic alterations, or changes to the epigenome. What is the epigenome? The epigenome corresponds to a set of chemical modifications to your genome that can tell...

A Matter of the Heart: Spermidine’s Protective Role in Cardiovascular Health

autophagy

A Matter of the Heart: Spermidine’s Protective Role in Cardiovascular Health

Spermidine is gaining recognition as a powerful bioactive compound for supporting cardiovascular health and longevity. As cardiovascular disease remains the leading cause of death worldwide, scientists are exploring novel, naturally...

Spermidine & Telomere Attrition

autophagy

Spermidine & Telomere Attrition

Telomere attrition is widely recognized as one of the primary hallmarks of aging, a concept introduced in the influential 2013 paper by López-Otín et al. titled "The Hallmarks of Aging."...

Spermidine & Genomic Instability

autophagy

Spermidine & Genomic Instability

The first hallmark of aging is genomic instability. Essentially, this means that as we get older, our cells start accumulating more and more genetic damage. This can lead to mutations,...

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