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Spermidine & Altered Intercellular Communication

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Spermidine & Altered Intercellular Communication

The Potential Benefits of Spermidine Supplementation on Sleep

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The Potential Benefits of Spermidine Supplementation on Sleep

Sleep is essential for maintaining brain health, emotional resilience, and metabolic balance. Yet as we age, sleep quality often deteriorates. These changes are not just inconveniences; they are risk factors...

Spermidine: The Unsung Hero Behind Rapamycin’s Longevity Boost

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Spermidine: The Unsung Hero Behind Rapamycin’s Longevity Boost

Rapamycin often steals the spotlight in longevity research, and for good reason. It’s a leading compound known to extend lifespan across species. Yet, quietly supporting rapamycin’s effects is another molecule:...

Spermidine & Mitochondrial Dysfunction

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Spermidine & Mitochondrial Dysfunction

As part of our continued exploration of how spermidine influences the 12 hallmarks of aging, this article focuses on the 7th hallmark: mitochondrial dysfunction.Aging is a multifaceted biological process marked...

Spermidine & Deregulated Nutrient Sensing

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Spermidine & Deregulated Nutrient Sensing

As we continue exploring the 12 hallmarks of aging, we turn our attention to the sixth: Deregulated Nutrient Sensing. This hallmark reflects how aging cells lose their ability to correctly interpret...

Spermidine & Disabled Macroautophagy

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Spermidine & Disabled Macroautophagy

Aging is a multifaceted biological process marked by the gradual decline of cellular and organismal functions. Among the hallmarks of aging, disabled macroautophagy plays a critical role in age-related deterioration....

Spermidine & Epigenetic Alterations

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Spermidine & Epigenetic Alterations

The third hallmark of aging is epigenetic alterations, or changes to the epigenome. What is the epigenome? The epigenome corresponds to a set of chemical modifications to your genome that can tell...

Spermidine & Telomere Attrition

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Spermidine & Telomere Attrition

Telomere attrition is widely recognized as one of the primary hallmarks of aging, a concept introduced in the influential 2013 paper by López-Otín et al. titled "The Hallmarks of Aging."...

Spermidine & Genomic Instability

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Spermidine & Genomic Instability

The first hallmark of aging is genomic instability. Essentially, this means that as we get older, our cells start accumulating more and more genetic damage. This can lead to mutations,...

Spermidine & the 12 Hallmarks of Aging

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Spermidine & the 12 Hallmarks of Aging

The 12 hallmarks of aging represent key biological processes that contribute to the gradual decline in cellular and organismal function over time. These hallmarks provide a framework for understanding how...

How Spermidine Can Promote Hair Growth and Reverse Grey Hair

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How Spermidine Can Promote Hair Growth and Reverse Grey Hair

Spermidine promotes hair growth by prolonging the anagen phase, stimulating hair follicle stem cell functions, and inducing autophagy and may be a powerful ally to reverse hair graying by increasing...

Spermidine: A Promising Molecule in the Fight Against Type 2 Diabetes

longevity

Spermidine: A Promising Molecule in the Fight Against Type 2 Diabetes

Type 2 diabetes (T2D) is a rapidly growing global health crisis, impacting over 537 million people worldwide. Despite advancements in treatment, the mechanisms behind its onset and progression remain complex...

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