Frequently Asked Questions (FAQs)


We've weighed in on our most frequently asked questions below. If you're looking for more detailed information, or if your questions isn't listed here, please visit our knowledge base or contact us.


What is Spermidine?

Spermidine is a naturally occurring “polyamine” that is present in ribosomes and living tissues. For more details about this fascinating compound, visit our spermidine information page.

Is Spermidine Safe to Eat?

Absolutely! It's likely that most of the food you eat every day as part of your normal diet naturally contain spermidine. Early studies even show that a spermidine-rich diet may contribute to a longer lifespan.

Where Does Your Spermidine Come From?

We scoured the earth to determine which spermidine-rich foods we should use to extract for spermidineLIFE®. Ultimately we found that spermidine-rich wheat germ is one of the highest concentrations of natural spermidine. We test our wheat germ before and after our proprietary extraction process to ensure our supplements are spermidine-rich, safe, and up to our quality standards.

For those interested in which foods contain the most spermidine, we put together a fact sheet on spermidine sources.

Why is spermidineLIFE® Good For You?

Early studies show that spermidineLIFE® may trigger the cellular process known as “autophagy” in our bodies. Studies have shown that autophagy could have a number of significant benefits for human cells.

We recommend that you always do your own research and always consult your doctor prior to taking any new supplement. We hope that our website will provide you a head-start on your research into spermidine and wheat germ extract.

What is in a spermidineLIFE® Capsule?

SpermidineLIFE® capsules contain natural wheat germ extract, zinc, and thiamine. To maintain quality control and product consistency, we create and coat our capsules with commonly used, food-safe ingredients: Hypromellose, and Calcium Carbonate.

I'm Allergic to Wheat, Can I Take spermidineLIFE®?

First and foremost, as always, we recommend that you consult with your doctor prior to taking any new supplement.

Though our product only contains around 1.36 mg of gluten per recommended daily dose, spermidineLIFE is naturally extracted from wheat germ. It will contain wheat and gluten.

If you are allergic to wheat or gluten, or you have a gluten insensitivity, we do not recommend taking spermidineLIFE®.

Can spermidineLIFE® Trigger Food Allergies?

We recommend that you consult with your doctor prior to taking any new supplement. spermidineLIFE capsules contain wheat germ extract, zinc, thiamine, Hypromellose, and Calcium Carbonate. spermidineLIFE® contains wheat. 

Does spermidineLIFE® Contain Gluten?

Yes, spermidineLIFE® contains wheat and gluten. spermidineLIFE® contains around 1,700 mg of gluten per 1kg of spermidineLIFE extract, or about 1.36mg of gluten per recommended daily dose. For context, a 1oz slice of white bread can contain over 3,500mg of gluten. We do not recommend spermidineLIFE® for those with gluten intolerance or coeliac disease.

Are spermidineLIFE® Capsules Vegetarian?

Yes! spermidineLIFE® capsules are vegetarian.

Are spermidineLIFE® Capsules Vegan?

Yes! spermidineLIFE® capsules are vegan.

Where Can I Buy Spermidine Supplements?

Spermidine is a naturally-occurring polyamine present in low amounts in many of the foods that you probably already eat. For those who wish to take additional spermidine as a dietary supplement, spermidineLIFE® is available on our online store here.

How Much Spermidine Should I Take Daily?

Early research leads us to recommend that everyone should consume increased levels of spermidine for life, to maintain optimum cellular performance and longevity.

Our recommended daily dose of spermidineLIFE® contains 1 mg of spermidine, and we third-party lab test every batch of spermidineLIFE® wheat germ extract to verify that our daily dose contains, indeed, 1 mg of spermidine.

As always, we recommend that you consult with your doctor prior to making changes to your diet or taking a new dietary supplement.  

How Long Does spermidineLIFE® Take to Work?

Your body will take time to adjust to increased levels of autophagy and reap the benefits of spermidine supplementation. Anecdotal reports and customer feedback have shown that it may take at least one month of spermidine supplementation at 1mg per day to begin to see positive indications.

Every human body is unique. We all have different diets, ages, health profiles, cellular stress levels, and health habits. For some, particularly those with health profiles that lead to consistent autophagy anyway, there may be little to no noticeable physiological changes within a 30-60 day cycle. This does not mean spermidine is doing nothing, it is simply further enhancing your healthy cellular lifestyle, which may not necessarily be a “change” for the healthiest among us. We know that spermidine levels decrease significantly with age, so older populations tend to “feel” spermidine supplementation faster and more acutely than younger populations.  

We recommend that you occasionally journal about your body’s reactions to spermidine supplementation. From our research and anecdotal reports, users may experience any of a number of the following physiological changes from improving cellular health through spermidine supplementation:

  • Increased hair/nail growth
  • Increased energy
  • Decreased inflammatory markers, often associated with point-specific injuries or cellular damage
  • Increased mental clarity
  • Increased deep sleep (as a proportion of overall sleep)
  • Increased immune-efficiency

This list is ongoing, both in research and in anecdotal reports. If you find something specific, drop us a line and let us know your own experience with spermidineLIFE®.

I'm a Diabetic, Should I Take spermidineLIFE®?

Early research shows that spermidine and spermidineLIFE® may have positive indications that may benefit many diabetics but as always, we recommend that you consult with your doctor prior to making changes to your diet or taking a new dietary supplement.

Will Taking spermidineLIFE® Break My Fast?

Officially, we must advise that you seek advice from a healthcare practitioner on this topic. Additionally, as you may find in your own research on the topic, the science is still not clearly settled on what exact type and amount of calories kicks our bodies out of autophagy.
That being said, it is generally recognized that the trigger for “ending” a fast is when the body creates an insulin response. While most of the contents of spermidineLIFE® clearly fall into the “healthy fats” category of the food groups, there is a tiny amount of carbohydrates in spermidineLIFE®, approximately 5mg per serving. From our early research, this volume is generally insufficient to trigger an insulin response; thus, spermidineLIFE® should not be considered a fast “breaker.”

Below are our general guidelines for spermidineLIFE® consumption while fasting:

Intermittent Fasting: If you are intermittent fasting, we recommend taking spermidineLIFE® with your last meal of the day to enhance your body’s move into ketosis and autophagy.

Extended (24+ hour) Wet Fast: Take spermidineLIFE® with water at the same time of day as you normally take it during an extended wet fast to enhance autophagy during your fast.

Extended Dry Fast: As liquid intake with spermidineLIFE® appears to aid in digestion, we do not recommend taking spermidineLIFE® during an extended dry fast. Resume taking spermidineLIFE® after your dry fast to ensure lasting benefits of autophagy.

How do I Store My spermidineLIFE®?

Store spermidineLIFE® in its original container in a cool, dry place. spermidineLIFE® will remain shelf-stable in this condition for 16+ months.

Extended exposure to direct sunlight, high humidity, or high temperatures (77+ degrees) can lead to degradation of the appearance and color of the extract (from testing we currently show no loss of effectiveness or spermidine content when product is contained in its original bottle and capsules). For highest effectiveness, storing in the refrigerator will ensure the most stable product.

Where is the Best Place to Find Information on Spermidine?

As always, we recommend that you consult with your doctor prior to making changes to your diet or taking a new dietary supplement. We also recommend that you thoroughly do your own research on spermidine and its positive indications prior to taking spermidineLIFE® or making changes to your diet. We hope that the resources provided to you on our website will be a good starting point for your research.

Additionally, studies on spermidine, autophagy, and spermidineLIFE® have been conducted globally and have been published in many readily available scientific journals. Other resources may be readily available online. As always, feel free to reach out via social media with any questions you may have that we might be able to assist with.

Still have questions? Visit the spermidineLIFE® Knowledge Base or reach out to us.