What is Nicotinamide Mononucleotide and How Does it Affect Aging in The Body?


What Is Nicotinamide Mononucleotide?

So, what is NMN or Nicotinamide Mononucleotide? (NMN) It is a nucleotide derived from ribose and nicotinamide. Nicotinamide is a form of vitamin B3, Niacin, and is often used as a dietary supplement and medication. You may be wondering what NMN supplement is? It’s a type of supplement that contains nicotinamide mononucleotide, a naturally-occurring molecule found in the body that helps to maintain cellular health and promote longevity. Nicotinamide research in mice has found that it may be a productive anti-aging agent. 

What Does NMN Do?

Researchers believe that NMN is one of the quickest ways to stimulate nicotinamide adenine dinucleotide (NAD). NAD is a coenzyme found in all cells and is linked with cell metabolism. It performs essential cell processes such as gene expression, chromosomal maintenance, and DNA repair. 

NMN is one of two strong precursors of NAD, the other being nicotinamide riboside (NR). NMN transforms into NR, which then enters human cells, converts back into NMN, and eventually converts to NAD. Researchers believe that there are more NMN and NR benefits than simply producing NAD. 

What Is NMN Good For?

One of the many NMN effects is that it can help promote autophagy. Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. This is great for those looking for NMN anti-aging remedies, as autophagy is essentially the body’s way of turning back the clock, creating younger cells. 

Research has also shown that NMN may protect the heart through autophagy. A study conducted on mice in 2014 found that NMN may protect the heart through stimulation of autophagy during myocardial ischemia. Other studies have found that NMN may help increase longevity and brain function by improving neurovascular coupling. 

Is NMN Safe?

It is completely normal to question NMN’s side effects to ensure its safety. However, if administered correctly, NMN supplements should be entirely safe. A single oral administration of NMN is safe and can be effectively metabolized in a healthy man without causing any significant deleterious effects. 

Foods that Contain NMN

After hearing about the benefits NMN posses and its anti-aging abilities, you’re going to want to take in as much NMN as possible. Luckily, there are plenty of fruits and vegetables that provide large amounts of MNM. In fact, it’s incredibly likely that these fruits and vegetables are already a staple in your diet. 

What Foods Contain NMN?

The study mentioned earlier found that older mice that drank water supplemented with NMN saw improvements in metabolism and energy reserves. Does this mean we can expect the same age-reversal effects seen in the study with the mice? Unfortunately, no. The supplement provided to the mice was much higher in NMN than vegetables and fruit are. While it may not be possible to eat enough fruits and vegetables to replicate the study, we can try. 

Here are foods that contain NMN:

  • Tomatoes
  • Avocados
  • Edamame
  • Broccoli
  • Cucumbers

As you can see, these foods are all commonplace in most kitchens. You have already implemented NMN into your diet without even knowing about it!

How Much NMN in a Daily Diet?

The general recommended dosage of NMN is anywhere between 250-1500 mg per day. Obviously, key contributing factors such as gender, age, height, and weight will play a role in determining the exact dosage. The reason why the dosage may seem high is that NMN is absorbed very quickly and has a short half-life. Because of this, it’s recommended that you try to keep your NAD levels as high as possible throughout the day. 

How Much Does NMN Cost?

This is going to depend on how you plan on consuming NMN. If you’re simply looking for an NMN rich diet, it’s going to cost however much avocados, tomatoes, or broccoli cost at your local supermarket. However, if you’re looking for an NMN supplement, those prices may vary. Most products are available for $5-$6 per gram while high-end products can reach as high as $15 per gram. 

Reverse the Effects of Aging

There are other supplements you can take that can reverse the effects of aging, including spermidineLIFE®. Spermidine is known to encourage cell regeneration in the body. This is the perfect companion for other healthy choices you are making in your life. Spermidine vs NMN is an important comparison when considering taking a supplement, as they both offer some of the same benefits but with different mechanisms of action. Please visit our shop to order this product today. 

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  • Don Moxley - Director of Applied Science

    Don Moxley is the Director of Applied Science at Longevity Labs. Moxley draws upon his career as an athlete, a sports scientist, and an instructor to lead and educate on the science of autophagy and longevity.