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Spermidine & Deregulated Nutrient Sensing

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Spermidine & Deregulated Nutrient Sensing

Spermidine & Disabled Macroautophagy

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Spermidine & Disabled Macroautophagy

Aging is a multifaceted biological process marked by the gradual decline of cellular and organismal functions. Among the hallmarks of aging, disabled macroautophagy plays a critical role in age-related deterioration....

Spermidine & Epigenetic Alterations

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Spermidine & Epigenetic Alterations

The third hallmark of aging is epigenetic alterations, or changes to the epigenome. What is the epigenome? The epigenome corresponds to a set of chemical modifications to your genome that can tell...

Spermidine & Telomere Attrition

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Spermidine & Telomere Attrition

Telomere attrition is widely recognized as one of the primary hallmarks of aging, a concept introduced in the influential 2013 paper by López-Otín et al. titled "The Hallmarks of Aging."...

Spermidine & Genomic Instability

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Spermidine & Genomic Instability

The first hallmark of aging is genomic instability. Essentially, this means that as we get older, our cells start accumulating more and more genetic damage. This can lead to mutations,...

Spermidine & the 12 Hallmarks of Aging

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Spermidine & the 12 Hallmarks of Aging

The 12 hallmarks of aging represent key biological processes that contribute to the gradual decline in cellular and organismal function over time. These hallmarks provide a framework for understanding how...

How Spermidine Can Promote Hair Growth and Reverse Grey Hair

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How Spermidine Can Promote Hair Growth and Reverse Grey Hair

Spermidine promotes hair growth by prolonging the anagen phase, stimulating hair follicle stem cell functions, and inducing autophagy and may be a powerful ally to reverse hair graying by increasing...

Spermidine: A Promising Molecule in the Fight Against Type 2 Diabetes

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Spermidine: A Promising Molecule in the Fight Against Type 2 Diabetes

Type 2 diabetes (T2D) is a rapidly growing global health crisis, impacting over 537 million people worldwide. Despite advancements in treatment, the mechanisms behind its onset and progression remain complex...

Unlocking the Fountain of Youth: How Fasting and Spermidine Team Up to Boost Health and Longevity

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Unlocking the Fountain of Youth: How Fasting and Spermidine Team Up to Boost Health and Longevity

In a groundbreaking study published in Nature Cell Biology, scientists reveal how spermidine is crucial to control autophagy during fasting and to unlock its health and longevity benefits.

Living to 120 - A Special Report on How to Slow Ageing

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Living to 120 - A Special Report on How to Slow Ageing

In September 2023, the Economist produced a review of the current methods employed and researched to slow aging in humans. The series of articles spanned a variety of background and...

A woman exercising to improve her cellular health

longevity

What Promotes Cellular Health?

Today, everyone is looking for newer ways to stay healthier and promote longevity. Cellular health, often overlooked, is one of the top areas that contributes to increased overall health. The...

Wheat germ that is high in spermidine

longevity

What is spermidine?

What Is Spermidine? Have you ever heard of spermidine? Spermidine is a natural occurring polyamine in the body. It  plays a major role in cellular health and function, primarily through...

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